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Advances in Protein NMR Impacting Drug Discovery Provided by the NIGMS Protein Structure Initiative

Rational drug design relies on three-dimensional structures of biological macromolecules, especially proteins. Structural genomics high-throughput (HTP) structure determination platforms established by the NIH Protein Structure Initiative are uniquely suited to provide these structures. NMR plays a...

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Bibliographic Details
Main Authors: Montelione, Gaetano T., Szyperski, Thomas
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002360/
https://ncbi.nlm.nih.gov/pubmed/20443167
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