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The darker side of follicular helper T cells: from autoimmunity to immunodeficiency

Follicular helper T (T(FH)) cells represent a distinct subset of CD4(+) helper T (T(H)) cells specialized in providing help to B cells. They are characterized by their unique transcriptional profile (Bcl6), surface marker expression (CXCR5, PD-1, ICOS and CD40L) and cytokine production pattern (IL-2...

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Hlavní autoři: Shekhar, Sudhanshu, Yang, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002332/
https://ncbi.nlm.nih.gov/pubmed/22885524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.26
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