Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells

AIM: To examine the regulatory crosstalk between the transcription factors Nrf2 and AP-1 in prostate cancer (PCa) by dietary cancer chemopreventive compounds (−)epigallocatechin-3-gallate (EGCG) from green tea and sulforaphane (SFN) from cruciferous vegetables. METHODS: We performed (i) in vitro stu...

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Autors principals: Nair, Sujit, Barve, Avantika, Khor, Tin-Oo, Shen, Guo-xiang, Lin, Wen, Chan, Jefferson Y, Cai, Li, Kong, Ah-Ng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002318/
https://ncbi.nlm.nih.gov/pubmed/20729872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.147
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