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Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors
Previous studies on lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) using various approaches have shown that both the molecules can act as intercellular signaling molecules. The discovery of the Edg subfamily of G-protein-coupled receptors (GPCRs) (later renamed LPA(1–3) and S1P(1–5))...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002311/ https://ncbi.nlm.nih.gov/pubmed/20729877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.135 |
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