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Inhibitory effects of rosiglitazone on paraquat-induced acute lung injury in rats

AIM: To investigate the effects of the PPAR-γ agonist rosiglitazone on acute lung injury induced by the herbicide paraquat (PQ) and the underlying mechanisms of action. METHODS: Male Sprague-Dawley rats were injected with PQ (20 mg/kg, ip). Rosiglitazone (3 or 10 mg/kg, ip) was administered 1 h befo...

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Detalhes bibliográficos
Main Authors: Liu, Zhen-ning, Zhao, Min, Zheng, Qiang, Zhao, Hong-yu, Hou, Wei-jian, Bai, Shu-ling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002157/
https://ncbi.nlm.nih.gov/pubmed/23933652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.65
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