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Sj7170, a Unique Dual-function Peptide with a Specific α-Chymotrypsin Inhibitory Activity and a Potent Tumor-activating Effect from Scorpion Venom

A new peptide precursor, termed Sj7170, was characterized from the venomous gland cDNA library of the scorpion Scorpiops jendeki. Sj7170 was deduced to be a 62-amino acid peptide cross-linked by five disulfide bridges. The recombinant Sj7170 peptide (rSj7170) with chromatographic purity was produced...

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Detalhes bibliográficos
Main Authors: Song, Yu, Gong, Ke, Yan, Hong, Hong, Wei, Wang, Le, Wu, Yingliang, Li, Wenhua, Li, Wenxin, Cao, Zhijian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002077/
https://ncbi.nlm.nih.gov/pubmed/24584937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.540419
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