Expression and activation of intracellular receptors TLR7, TLR8 and TLR9 in peripheral blood monocytes from HIV-infected patients

INTRODUCTION: TLR´s play a role in host defense in HIV infection recognizing the viral DNA or RNA. Their activation induces a signaling pathway that includes the proteins MyD88, IRAK4, TRAF6 and the transcription factor NF-kBp65. OBJECTIVE: To determine the expression of TLR7, TLR8 and TLR9, and act...

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Bibliografiska uppgifter
Huvudupphovsmän: Valencia Pacheco, Guillermo J, Pinzón Herrera, Francisc, Cruz López, Juan J, Vera Gamboa, Ligia del Carmen, Pavía Ruiz, Norma, Santos Rivero, Adrián, Sánchez Lugo, Saulo, Puerto, Fernando
Materialtyp: Artigo
Språk:Inglês
Publicerad: Universidad del Valle 2013
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002021/
https://ncbi.nlm.nih.gov/pubmed/24892454
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