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Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry

A convenient and efficient (one-step) oxidation is reported of commercially available tosylmethylisocyanide (TOSMIC) to form tosylmethylisocyanate, making this highly reactive bifunctional molecule a readily available synthetic reagent. Besides engaging in nucleophilic addition reactions with alcoho...

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Détails bibliographiques
Auteurs principaux: Le, Hoang V., Ganem, Bruce
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001987/
https://ncbi.nlm.nih.gov/pubmed/24791030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.02.016
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