Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1(*)

AIM: To examine the effects of triptolide (TPL) on T-cell leukemia cells and identify their underlying mechanisms. METHODS: The cytotoxicity of TPL was assessed by MTT assay. Cell apoptosis was determined using annexin V and DAPI staining and analyzed by flow cytometry or fluorescence microscopy. Th...

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Main Authors: Meng, Hai-tao, Zhu, Li, Ni, Wan-mao, You, Liang-shun, Jin, Jie, Qian, Wen-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001980/
https://ncbi.nlm.nih.gov/pubmed/21441948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.237
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