Apoptosis induced by genipin in human leukemia K562 cells: involvement of c-Jun N-terminal kinase in G(2)/M arrest

AIM: To investigate the effect of genipin on apoptosis in human leukemia K562 cells in vitro and elucidate the underlying mechanisms. METHODS: The effect of genipin on K562 cell viability was measured using trypan blue dye exclusion and cell counting. Morphological changes were detected using phase-...

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Autores principales: Feng, Qian, Cao, Hou-li, Xu, Wei, Li, Xiao-rong, Ren, Yan-qin, Du, Lin-fang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001971/
https://ncbi.nlm.nih.gov/pubmed/21399655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.158
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