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A local glutamate-glutamine cycle sustains synaptic excitatory transmitter release

Biochemical studies suggest that excitatory neurons are metabolically coupled with astrocytes to generate glutamate for release. However, the extent to which glutamatergic neurotransmission depends on this process remains controversial, as direct electrophysiological evidence is lacking. The distanc...

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Библиографические подробности
Главные авторы: Tani, Hiroaki, Dulla, Chris G., Farzampour, Zoya, Taylor-Weiner, Amaro, Huguenard, John R., Reimer, Richard J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001919/
https://ncbi.nlm.nih.gov/pubmed/24559677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.026
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