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Ex vivo, microelectrode analysis of conduction through the AV node of wild‐type and Nkx2‐5 mutant mouse hearts as guided by a Cx40‐eGFP transgenic reporter

Mutations of the cardiac transcription factor NKX2‐5 cause hypoplastic development of the AV node and conduction block. How the anatomy of the mutant AV node relates to its function is unknown. We thus studied conduction through the AV nodal region in ex vivo preparations of wild‐type and Nkx2‐5(+/−...

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Detalhes bibliográficos
Main Authors: Gazit, Avihu Z., Li, Alex, Choi, Jacob S., Miquerol, Lucile, Jay, Patrick Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001877/
https://ncbi.nlm.nih.gov/pubmed/24771692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.285
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