Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart

Diabetic cardiomyopathy is a secondary complication of diabetes with an unclear etiology. Based on a functional genomic evaluation of obesity-associated cardiac gene expression, we previously identified and cloned the gene encoding apolipoprotein O (APOO), which is overexpressed in hearts from diabe...

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Detalhes bibliográficos
Main Authors: Turkieh, Annie, Caubère, Céline, Barutaut, Manon, Desmoulin, Franck, Harmancey, Romain, Galinier, Michel, Berry, Matthieu, Dambrin, Camille, Polidori, Carlo, Casteilla, Louis, Koukoui, François, Rouet, Philippe, Smih, Fatima
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001558/
https://ncbi.nlm.nih.gov/pubmed/24743151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74668
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