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Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis
Allan-Herndon-Dudley syndrome (AHDS), a severe form of psychomotor retardation with abnormal thyroid hormone (TH) parameters, is linked to mutations in the TH-specific monocarboxylate transporter MCT8. In mice, deletion of Mct8 (Mct8 KO) faithfully replicates AHDS-associated endocrine abnormalities;...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001533/ https://ncbi.nlm.nih.gov/pubmed/24691440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70324 |
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