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Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E

Cucurbitacin E (CuE) or α-elaterin is a natural compound previously shown to be an antifeedant as well as a potent chemopreventive agent against several types of cancer. The present study investigated the anticancer effects of CuE on colorectal cancer (CRC) using primary cell lines isolated from fiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hsu, Y-C, Huang, T-Y, Chen, M-J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001305/
https://ncbi.nlm.nih.gov/pubmed/24763055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.151
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