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Orally administered DTPA penta-ethyl ester for the decorporation of inhaled (241)Am

Diethylenetriaminepentaacetic acid (DTPA) is an effective decorporation agent to facilitate the elimination of radionuclides from the body, but its permeability-limited oral bioavailability limits its utility in mass-casualty emergencies. To overcome this limitation, a prodrug strategy using the pen...

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Autors principals: Sueda, Katsuhiko, Sadgrove, Matthew P., Huckle, James E., Leed, Marina G. D., Weber, Waylon M., Doyle-Eisele, Melanie, Guilmette, Raymond A., Jay, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001124/
https://ncbi.nlm.nih.gov/pubmed/24619514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23932
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