Silymarin improved 6-OHDA-induced motor impairment in hemi-parkisonian rats: behavioral and molecular study

BACKGROUND: Neuroinflammation and oxidative stress has been shown to be associated with the development of Parkinson disease (PD). In the present study, we investigated the effect of intraperitoneal (i.p.) administration of silymarin, on 6-OHDA-induced motor-impairment, brain lipid per-oxidation and...

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Autori principali: Haddadi, Rasool, Nayebi, Alireza Mohajjel, Farajniya, Safar, Brooshghalan, Shahla Eyvari, Sharifi, Hamdolah
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001109/
https://ncbi.nlm.nih.gov/pubmed/24726284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-38
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