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Stable RNA interference rules for silencing

RNA interference has become an indispensable tool for loss-of-function studies across eukaryotes. By enabling stable and reversible gene silencing, shRNAs provide a means to study long-term phenotypes, perform pool-based forward genetic screens and examine the consequences of temporary target inhibi...

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Autori principali: Fellmann, Christof, Lowe, Scott W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001088/
https://ncbi.nlm.nih.gov/pubmed/24366030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2895
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