Molecular Analysis of Ciprofloxacin Resistance Mechanisms in Malaysian ESBL-Producing Klebsiella pneumoniae Isolates and Development of Mismatch Amplification Mutation Assays (MAMA) for Rapid Detection of gyrA and parC Mutations

Ninety-three Malaysian extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae isolates were investigated for ciprofloxacin resistance. Two mismatch amplification mutation (MAMA) assays were developed and used to facilitate rapid detection of gyrA and parC mutations. The isolates were a...

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Main Authors: Al-Marzooq, Farah, Mohd Yusof, Mohd Yasim, Tay, Sun Tee
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000930/
https://ncbi.nlm.nih.gov/pubmed/24860827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/601630
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