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Pharmacogenomics of Sterol Synthesis and Statin Use in Schizophrenia Subjects Treated With Antipsychotics

OBJECTIVE: Patients with schizophrenia, treated with antipsychotics often develop metabolic side effects including dyslipidemia. Antipsychotics potentially upregulate gene expression of a lipid metabolism pathyway called sterol regulatory element binding protein (SREBP) via transcription factors (SR...

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Détails bibliographiques
Auteurs principaux: Vassas, Thomas J., Burghardt, Kyle J., Ellingrod, Vicki L.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000704/
https://ncbi.nlm.nih.gov/pubmed/24329191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.157
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