Inhibition of calpains fails to improve regeneration through a peripheral nerve conduit

Intramuscular injection of the calpain inhibitor leupeptin promotes peripheral nerve regeneration in primates (Badalamente et al., 1989 [13]), and direct positive effects of leupeptin on axon outgrowth were observed in vitro (Hausott et al., 2012 [12]). In this study, we applied leupeptin (2 mg/ml)...

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Main Authors: Hausner, Thomas, Marvaldi, Letizia, Márton, Gábor, Pajer, Krisztián, Hopf, Rudolf, Schmidhammer, Robert, Hausott, Barbara, Redl, Heinz, Nógrádi, Antal, Klimaschewski, Lars
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Scientific Publishers Ireland 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000267/
https://ncbi.nlm.nih.gov/pubmed/24631569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.03.009
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