Canine Distemper Virus Infection Leads to an Inhibitory Phenotype of Monocyte-Derived Dendritic Cells In Vitro with Reduced Expression of Co-Stimulatory Molecules and Increased Interleukin-10 Transcription

Canine distemper virus (CDV) exhibits a profound lymphotropism that causes immunosuppression and increased susceptibility of affected dogs to opportunistic infections. Similar to human measles virus, CDV is supposed to inhibit terminal differentiation of dendritic cells (DCs), responsible for distur...

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Detalhes bibliográficos
Main Authors: Qeska, Visar, Barthel, Yvonne, Herder, Vanessa, Stein, Veronika M., Tipold, Andrea, Urhausen, Carola, Günzel-Apel, Anne-Rose, Rohn, Karl, Baumgärtner, Wolfgang, Beineke, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000198/
https://ncbi.nlm.nih.gov/pubmed/24769532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096121
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