Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status

BACKGROUND: The aim was to assess and compare prognostic power of nine breast cancer gene signatures (Intrinsic, PAM50, 70-gene, 76-gene, Genomic-Grade-Index, 21-gene-Recurrence-Score, EndoPredict, Wound-Response and Hypoxia) in relation to ER status and follow-up time. METHODS: A gene expression da...

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Main Authors: Zhao, Xi, Rødland, Einar Andreas, Sørlie, Therese, Vollan, Hans Kristian Moen, Russnes, Hege G, Kristensen, Vessela N, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000128/
https://ncbi.nlm.nih.gov/pubmed/24645668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-211
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