DNA methylation alterations in grade II- and anaplastic pleomorphic xanthoastrocytoma

BACKGROUND: Pleomorphic xanthoastrocytoma (PXA) is a rare WHO grade II tumor accounting for less than 1% of all astrocytomas. Malignant transformation into PXA with anaplastic features, is unusual and correlates with poorer outcome of the patients. METHODS: Using a DNA methylation custom array, we h...

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Autori principali: Martínez, Ramón, Carmona, F Javier, Vizoso, Miguel, Rohde, Veit, Kirsch, Matthias, Schackert, Gabriele, Ropero, Santiago, Paulus, Werner, Barrantes, Alonso, Gomez, Antonio, Esteller, Manel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000050/
https://ncbi.nlm.nih.gov/pubmed/24650279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-213
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