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Characterization of a SAM-dependent fluorinase from a latent biosynthetic pathway for fluoroacetate and 4-fluorothreonine formation in Nocardia brasiliensis

Fluorination has been widely used in chemical synthesis, but is rare in nature. The only known biological fluorination scope is represented by the fl pathway from Streptomyces cattleya that produces fluoroacetate (FAc) and 4-fluorothreonine (4-FT). Here we report the identification of a novel pathwa...

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Main Authors: Wang, Yaya, Deng, Zixin, Qu, Xudong
Formato: Artigo
Idioma:Inglês
Publicado: F1000Research 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999930/
https://ncbi.nlm.nih.gov/pubmed/24795808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3-61.v1
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