A carregar...
Group-assisted purification (GAP) chemistry for the synthesis of Velcade via asymmetric borylation of N-phosphinylimines
A new approach to the anticancer drug Velcade was developed by performing asymmetric borylation of an imine anchored with a chiral N-phosphinyl auxiliary. Throughout the 7-step synthesis, especially in the imine’s synthesis and in the asymmetric borylation reactions, operations and work-up were cond...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999766/ https://ncbi.nlm.nih.gov/pubmed/24778728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.69 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|