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Microtubule-targeting agents in oncology and therapeutic potential in hepatocellular carcinoma
In mammalian cells, microtubules are present both in interphase and dividing cells. In the latter, microtubules forming the mitotic spindle are highly dynamic and exquisitely sensitive to therapeutic inhibitors. Developed to alter microtubule function, microtubule-binding agents have been proven to...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999274/ https://ncbi.nlm.nih.gov/pubmed/24790457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S46019 |
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