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Thrombotic Microangiopathy In Metastatic Melanoma Patients Treated with Adoptive Cell Therapy and Total Body Irradiation

BACKGROUND: Thrombotic microangioapathy (TMA) is a complication that developed in some patients receiving 12 Gy total body irradiation in addition to lymphodepleting preparative chemotherapy prior to infusion of autologous tumor infiltrating lymphocytes (TIL) with high-dose aldesleukin (IL-2). This...

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Main Authors: Tseng, Jennifer, Citrin, Deborah E., Waldman, Meryl, White, Donald E., Rosenberg, Steven A., Yang, James C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999204/
https://ncbi.nlm.nih.gov/pubmed/24474396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28547
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