Effects of smoking and alcohol consumption on 5-fluorouracil-related metabolic enzymes in oral squamous cell carcinoma

Lifestyle, particularly smoking and alcohol consumption, may induce and/or inhibit drug metabolism. In order to reveal the effects of smoking and alcohol consumption on the 5-fluorouracil (5-FU)-related metabolic enzymes, namely thymidylate synthase, dihydropyrimidine dehydrogenase (DPD; a sole cata...

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Main Authors: YAMASHITA, TOMOMI, KATO, KEIZO, LONG, NGUYEN KHANH, MAKITA, HIROKI, YONEMOTO, KAZUHIRO, IIDA, KAZUKI, TAMAOKI, NARITAKA, HATAKEYAMA, DAIJIRO, SHIBATA, TOSHIYUKI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999128/
https://ncbi.nlm.nih.gov/pubmed/24772313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2014.267
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