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Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders.

There is increasing evidence for an important role of adverse early experience on the development of major psychiatric disorders in adulthood. Corticotropin-releasing factor (CRF), an endogenous neuropeptide, is the primary physiological regulator of the mammalian stress response. Grown nonhuman pri...

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Detalhes bibliográficos
Main Authors: Coplan, J D, Andrews, M W, Rosenblum, L A, Owens, M J, Friedman, S, Gorman, J M, Nemeroff, C B
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39991/
https://ncbi.nlm.nih.gov/pubmed/8643680
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