Longer Telomere Length in COPD Patients with α(1)-Antitrypsin Deficiency Independent of Lung Function

Oxidative stress is involved in the pathogenesis of airway obstruction in α(1)-antitrypsin deficient patients. This may result in a shortening of telomere length, resulting in cellular senescence. To test whether telomere length differs in α(1)-antitrypsin deficient patients compared with controls,...

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Main Authors: Saferali, Aabida, Lee, Jee, Sin, Don D., Rouhani, Farshid N., Brantly, Mark L., Sandford, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998943/
https://ncbi.nlm.nih.gov/pubmed/24763308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095600
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