Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation

How the immune system senses aeroallergens and triggers an aberrant inflammation is poorly understood. Dectin-2 is a house dust mite (HDM)-sensing pattern recognition receptor. In a 3-week mouse model of repeated intranasal HDM challenge, anti-Dectin-2 potently attenuated the characteristic allergic...

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Main Authors: Clarke, D L, Davis, N H E, Campion, C L, Foster, M L, Heasman, S C, Lewis, A R, Anderson, I K, Corkill, D J, Sleeman, M A, May, R D, Robinson, M J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998635/
https://ncbi.nlm.nih.gov/pubmed/24129160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.74
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