Immunological Visibility: Posttranscriptional Regulation of Human NKG2D Ligands by the EGF Receptor Pathway

Human cytolytic T lymphocytes and NK cells can limit tumor growth and are being increasingly harnessed for tumor immunotherapy. One way cytolytic lymphocytes recognize tumor cells is by engagement of their activating receptor, NKG2D, by stress-antigens of the MICA/B and ULBP families. This study sho...

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Autori principali: Vantourout, Pierre, Willcox, Carrie, Turner, Andrea, Swanson, Chad, Haque, Yasmin, Sobolev, Olga, Grigoriadis, Anita, Tutt, Andrew, Hayday, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998197/
https://ncbi.nlm.nih.gov/pubmed/24718859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007579
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