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Effects of modulators of AMP-activated protein kinase on TASK-1/3 and intracellular Ca(2+) concentration in rat carotid body glomus cells

Acute hypoxia depolarizes carotid body chemoreceptor (glomus) cells and elevates intracellular Ca(2+) concentration ([Ca(2+)](i)). Recent studies suggest that AMP-activated protein kinase (AMPK) mediates these effects of hypoxia by inhibiting the background K(+) channels such as TASK. Here we studie...

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Detalhes bibliográficos
Main Authors: Kim, Donghee, Kang1,2, Dawon, Martin, Elizabeth A., Kim, Insook, Carroll, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998119/
https://ncbi.nlm.nih.gov/pubmed/24530802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2014.01.020
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