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Dual Inhibitory Pathways of Metallofullerenol Gd@C(82)(OH)(22) on Matrix Metalloproteinase-2: Molecular insight into drug-like nanomedicine
Cancer metastasis is an important criterion to evaluate tumor malignancy. Matrix metalloproteinases (MMPs) play a crucial role in cancer proliferation and migration by virtue of their proteolytic functions in angiogenesis and extracelluar matrix (ECM) degradation, making them potential targets of an...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3998016/ https://ncbi.nlm.nih.gov/pubmed/24758941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04775 |
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