The Relationship between the Antitumor Effect of the IL-12 Gene Therapy and the Expression of Th1 Cytokines in an HPV16-Positive Murine Tumor Model

Objective. The goal of the present study was to investigate the effect of IL-12 expressed in plasmid on the Th1 cytokine profile in an experimental HPV16-positive murine tumor model and the association with the IL-12's antitumor effect. Methods. Mice were injected with BMK-16/myc cells to estab...

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Detalhes bibliográficos
Main Authors: García Paz, Flor, Madrid Marina, Vicente, Morales Ortega, Ausencio, Santander González, Abimelec, Peralta Zaragoza, Oscar, Burguete García, Ana, Torres Poveda, Kirvis, Moreno, José, Alcocer González, Juan, Hernandez Marquez, Eva, Bermúdez Morales, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997981/
https://ncbi.nlm.nih.gov/pubmed/24808638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/510846
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