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T cell receptor-Vβ repertoires in lung and blood CD4(+) and CD8(+) T cells of pulmonary sarcoidosis patients

BACKGROUND: Sarcoidosis patients have accumulations of activated CD4(+) T cells in affected organs, such as the lungs. T cell receptor (TCR) Vβ-chain usage has been incompletely characterized in these patients. METHODS: We surveyed the TCR Vβ usage in CD4(+) and CD8(+) T cells in bronchoalveolar lav...

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Main Authors: Ahlgren, Kerstin M, Ruckdeschel, Tina, Eklund, Anders, Wahlström, Jan, Grunewald, Johan
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997965/
https://ncbi.nlm.nih.gov/pubmed/24656074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-50
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