p16(INK4A) and p14(ARF) Gene Promoter Hypermethylation as Prognostic Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma: A Review

Head and neck squamous cell carcinoma is a heterogeneous group of tumors with each subtype having a distinct histopathological and molecular profile. Most tumors share, to some extent, the same multistep carcinogenic pathways, which include a wide variety of genetic and epigenetic changes. Epigeneti...

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Detalhes bibliográficos
Main Authors: Al-Kaabi, A., van Bockel, L. W., Pothen, A. J., Willems, S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997957/
https://ncbi.nlm.nih.gov/pubmed/24803719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/260549
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