Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target

BACKGROUND: Based on resistance of currently used anti-malarials, a new anti-malarial drug target against Plasmodium falciparum is urgently needed. Damaged DNA cannot be transcribed without prior DNA repair; therefore, uracil-DNA glycosylase, playing an important role in base excision repair, may ac...

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Main Authors: Suksangpleng, Thidarat, Leartsakulpanich, Ubolsree, Moonsom, Saengduen, Siribal, Saranya, Boonyuen, Usa, Wright, George E, Chavalitshewinkoon-Petmitr, Porntip
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997752/
https://ncbi.nlm.nih.gov/pubmed/24742318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-149
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