Effect of the LPA-mediated CXCL12-CXCR4 axis in the tumor proliferation, migration and invasion of ovarian cancer cell lines

Ovarian cancer is the most fatal gynecological cancer, with a 5-year survival rate of only 30%. Lysophosphatidic acid (LPA), which possesses growth factor-like functions, is a major regulatory factor in the peritoneal metastasis of ovarian cancer. LPA stimulates the expression of numerous genes that...

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Bibliographic Details
Main Authors: WANG, HUI, LIU, WENLI, WEI, DONGMIN, HU, KUN, WU, XIAOHUA, YAO, YUANQING
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997722/
https://ncbi.nlm.nih.gov/pubmed/24765180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.1926
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