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Novel PPAR Pan Agonist, ZBH Ameliorates Hyperlipidemia and Insulin Resistance in High Fat Diet Induced Hyperlipidemic Hamster

Effective and safe pharmacological interventions for hyperlipidemia remains badly needed. By incorporating the key pharmacophore of fibrates into the natural scaffold of resveratrol, a novel structural compound ZBH was constructed. In present study, we found ZBH reserved approximately one third of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Wei, Fan, Shiyong, Xie, Xinni, Xue, Nina, Jin, Xueyuan, Wang, Lili
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997506/
https://ncbi.nlm.nih.gov/pubmed/24759758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096056
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