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Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain

The pathogenesis of diabetic neurological complications is not fully understood. Diabetes mellitus (DM) and Alzheimer's disease (AD) are characterized by amyloid deposits. Glycogen synthase kinase-3 (GSK-3) plays an important role in the pathogenesis of AD and DM. Here we tried to investigate t...

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Bibliografiske detaljer
Main Authors: Qu, Zhong-Sen, Li, Liang, Sun, Xiao-Jiang, Zhao, Yu-Wu, Zhang, Jin, Geng, Zhi, Fu, Jian-Liang, Ren, Qing-Guo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997149/
https://ncbi.nlm.nih.gov/pubmed/24983010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/878123
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