Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potential

Hypoxia inducible factor-1α (HIF-1α) plays an important role in angiogenesis-osteogenesis coupling during bone regeneration, which can enhance the bone healing capacity of mesenchymal stem cells (MSCs) by improving their osteogenic and angiogenic activities. Previous studies transduced the HIF-1α ge...

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Autors principals: Ding, Hao, Gao, You-Shui, Wang, Yang, Hu, Chen, Sun, Yuan, Zhang, Changqing
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996975/
https://ncbi.nlm.nih.gov/pubmed/24328551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0486
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