Mitochondrial Uncoupling Protein 2 Induces Cell Cycle Arrest and Necrotic Cell Death

Uncoupling protein 2 (UCP2) is a mitochondrial membrane protein that regulates energy metabolism and reactive oxygen species (ROS) production. We generated mouse carboxy- and amino-terminal green fluorescent protein (GFP)-tagged UCP2 constructs to investigate the effect of UCP2 expression on cell pr...

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Autori principali: Palanisamy, Arun P., Cheng, Gang, Sutter, Alton G., Evans, Zachary P., Polito, Carmen C., Jin, Lan, Liu, John, Schmidt, Michael G., Chavin, Kenneth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996969/
https://ncbi.nlm.nih.gov/pubmed/24320727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/met.2013.0096
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