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Cerulenin inhibits unsaturated fatty acids synthesis in Bacillus subtilis by modifying the input signal of DesK thermosensor

Bacillus subtilis responds to a sudden decrease in temperature by transiently inducing the expression of the des gene encoding for a lipid desaturase, Δ5-Des, which introduces a double bond into the acyl chain of preexisting membrane phospholipids. This Δ5-Des-mediated membrane remodeling is control...

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Détails bibliographiques
Auteurs principaux: Porrini, Lucía, Cybulski, Larisa E, Altabe, Silvia G, Mansilla, María C, de Mendoza, Diego
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons Ltd. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996569/
https://ncbi.nlm.nih.gov/pubmed/24574048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.154
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