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Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen

Permanent stop-and-shop large-scale mouse mutant resources provide an excellent platform to decipher tissue phenogenomics. Here we analyse skin from 538 knockout mouse mutants generated by the Sanger Institute Mouse Genetics Project. We optimize immunolabelling of tail epidermal wholemounts to allow...

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Detalhes bibliográficos
Main Authors: Liakath-Ali, Kifayathullah, Vancollie, Valerie E., Heath, Emma, Smedley, Damian P., Estabel, Jeanne, Sunter, David, DiTommaso, Tia, White, Jacqueline K., Ramirez-Solis, Ramiro, Smyth, Ian, Steel, Karen P., Watt, Fiona M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996542/
https://ncbi.nlm.nih.gov/pubmed/24721909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4540
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