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The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages

BACKGROUND: Immune system dysregulation is well-recognized in autism and thought to be part of the etiology of this disorder. The endocannabinoid system is a key regulator of the immune system via the cannabinoid receptor type 2 (CB2R) which is highly expressed on macrophages and microglial cells. W...

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Bibliografske podrobnosti
Main Authors: Siniscalco, Dario, Bradstreet, James Jeffrey, Cirillo, Alessandra, Antonucci, Nicola
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996516/
https://ncbi.nlm.nih.gov/pubmed/24739187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-78
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