Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus challenge in SCID mice

BACKGROUND: Convalescent plasma and fractionated immunoglobulins have been suggested as prophylactic or therapeutic interventions during an influenza pandemic. FINDINGS: Intravenous immunoglobulin (IVIG) preparations manufactured from human plasma collected before the 2009 H1N1 influenza pandemic, a...

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Detalhes bibliográficos
Main Authors: Hohenadl, Christine, Wodal, Walter, Kerschbaum, Astrid, Fritz, Richard, Howard, M Keith, Farcet, Maria R, Portsmouth, Daniel, McVey, John K, Baker, Donald A, Ehrlich, Hartmut J, Barrett, P Noel, Kreil, Thomas R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996311/
https://ncbi.nlm.nih.gov/pubmed/24739285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-70
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