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Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function

Nicotinamide adenine dinucleotide (NAD(+)) is an enzyme cofactor or cosubstrate in many essential biological pathways. To date, the primary source of neuronal NAD(+) has been unclear. NAD(+) can be synthesized from several different precursors, among which nicotinamide is the substrate predominantly...

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Detalhes bibliográficos
Main Authors: Stein, Liana Roberts, Wozniak, David F., Dearborn, Joshua T., Kubota, Shunsuke, Apte, Rajendra S., Izumi, Yukitoshi, Zorumski, Charles F., Imai, Shin-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996209/
https://ncbi.nlm.nih.gov/pubmed/24760840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4730-13.2014
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