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Doing without codeine: why and what are the alternatives?

Codeine is a mild opioid widely used as an analgesic in various age groups, including various pediatric settings. It is a prodrug that owes its analgesic effect almost entirely to the principal metabolite: morphine. The genetic polymorphisms can contribute to making the pharmacokinetics of codeine h...

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Hlavní autoři: Benini, Franca, Barbi, Egidio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996141/
https://ncbi.nlm.nih.gov/pubmed/24517264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1824-7288-40-16
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